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80,000 Cholera Cases and 1,400 Deaths Spark Humanitarian Catastrophe in South Sudan

South Sudan grapples with its worst cholera outbreak, with over 80,000 cases and 1,400 deaths reported in a humanitarian crisis exacerbated by violence and climate change. The combination of political inaction and funding shortfalls threatens to worsen the situation further.

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80,000 Cholera Cases and 1,400 Deaths Spark Humanitarian Catastrophe in South Sudan
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South Sudan Faces Unprecedented Cholera Crisis

As South Sudan approaches its fourteenth independence anniversary, it finds itself in the throes of its longest and deadliest cholera outbreak. Since its onset in September 2024, the outbreak has spiraled into a humanitarian disaster, with over 80,000 cases and 1,400 deaths reported as of July 2025. The combination of rising intercommunal violence, flooding, and catastrophic hunger has created a perfect storm for the spread of this preventable disease.

Political Inaction Fuels Health Crisis

The cholera outbreak is symptomatic of deeper systemic failures. According to research on health priorities in South Sudan, political instability has severely hampered the effectiveness of public health initiatives. The UN Resident and Humanitarian Coordinator, Anita Kiki Gbeho, emphasized the urgent need for collective action to resolve political tensions. However, the ongoing conflict and lack of cohesive governance continue to obstruct efforts aimed at alleviating this crisis.

South Sudan extends transitional government by two years ...

South Sudan extends transitional government by two years ...

Impacts of Climate Change on Public Health

Flooding exacerbates the cholera outbreak, doubling the frequency of such health emergencies. Rising global temperatures have intensified these floods, pushing millions of South Sudanese into regions previously deemed safe from cholera. The UN has warned that without immediate action, the situation could deteriorate further. Access to clean water is already jeopardized, making it even more crucial to improve sanitation infrastructure as highlighted in a study on health systems strengthening in South Sudan.

Funding Shortfalls Leave Millions at Risk

The humanitarian response is critically underfunded. With a required $1.69 billion to address multiple intersecting needs, only $368 million has been secured so far. This funding gap threatens the viability of cholera response initiatives, including vaccination campaigns and sanitation improvements. As stated in the ministers' communiqué, cholera response and flood preparedness must be urgent national priorities. However, the lack of financial resources undermines these essential efforts.

South Sudan: MSF calls for urgent action as cholera outbreak ...

South Sudan: MSF calls for urgent action as cholera outbreak ...

The Human Cost of Cholera

Cholera is a preventable disease, yet its impact is devastating in South Sudan. The symptoms often include severe diarrhea, which can lead to death within hours if not treated promptly. The current outbreak highlights the urgent need for effective health policies that prioritize access to clean water and sanitation. Despite being treatable with oral rehydration salts, the public health system is stretched thin, lacking the resources and infrastructure to manage such crises. As reported by WHO, the cholera situation is dire, with 44 counties already affected.

While cholera is often seen as an isolated public health issue, its prevalence in South Sudan reveals the intersection of health, politics, and climate. As long as governance remains weak and resources are scarce, South Sudan will continue to experience health crises that could be mitigated with adequate funding and systematic changes.