A new study has established a troubling link between the oral bacterium Fusobacterium nucleatum and preeclampsia, a serious pregnancy complication. Researchers from Washington University School of Medicine in St. Louis found that this bacterium can infiltrate the placenta, leading to inflammation that may result in premature birth, low birth weight, and even death.
Published in the journal Nature, the study analyzed placenta samples from women diagnosed with preeclampsia and detected the presence of Fusobacterium nucleatum along with associated inflammatory markers. This finding builds on existing knowledge that the bacterium is also implicated in the development of colorectal cancer, highlighting its potential systemic effects when it spreads from the mouth to other parts of the body.
The implications of this research are significant, as it paves the way for new diagnostic and treatment strategies aimed at combating preeclampsia. Future studies will investigate how Fusobacterium nucleatum interacts with the maternal immune system and explore preventative measures to curb its spread.
This research comes at a critical time, as preeclampsia affects approximately 5-8% of pregnancies worldwide, posing serious risks to both mothers and infants. As previously reported, understanding the role of oral health in pregnancy may be vital for improving maternal and fetal outcomes.