U.S. and Syrian Forces Destroy Over 15 ISIS Weapons Sites in Southern Syria
In a significant military operation, U.S. Central Command (CENTCOM) and the Syrian Ministry of Interior successfully located and destroyed more than 15 sites containing weapons caches belonging to the Islamic State (ISIS) in southern Syria. This operation took place from November 24 to November 27, 2025, primarily in the Rif Damashq province, an area that has been a focal point of conflict and insurgency in the region.
Key Details
The operation was conducted by U.S. military personnel from the Combined Joint Task Force – Operation Inherent Resolve (CJTF-OIR), which is the coalition established to defeat ISIS. Working in close collaboration with Syrian forces, the task force identified and targeted the ISIS weapons storage facilities through a series of coordinated airstrikes and ground detonations.
During this operation, the coalition forces successfully destroyed a substantial amount of weaponry, including:
- Over 130 mortars and rockets
- Multiple assault rifles
- Machine guns
- Anti-tank mines
- Materials intended for the construction of improvised explosive devices (IEDs)
In addition to the weapons caches, the forces also discovered and destroyed illicit drugs, further contributing to the disruption of ISIS"s operational capabilities in the region. The destruction of these materials is seen as a critical step in undermining the group"s ability to conduct attacks and maintain its presence in southern Syria.
Background
The ongoing conflict in Syria has seen the rise and fall of various extremist groups, with ISIS being one of the most notorious. Although the group has lost significant territory since its peak in 2014, it continues to pose a threat through sleeper cells and sporadic attacks. The collaboration between U.S. forces and Syrian authorities is part of a broader strategy to stabilize the region and prevent the resurgence of ISIS.
The Rif Damashq province, where the operation took place, has been a critical battleground in the fight against ISIS and other militant groups. The area has experienced continuous military operations aimed at dismantling the infrastructure that supports these organizations.
What"s Next
The successful execution of this operation highlights the ongoing commitment of U.S. and allied forces to combat ISIS and enhance security in Syria. As previously reported, the situation in the region remains fluid, with various factions vying for control and influence. The destruction of these weapons caches is expected to have a short-term impact on ISIS"s operational capabilities, but the long-term effectiveness of such operations will depend on continued intelligence sharing and military cooperation between the U.S. and Syrian forces.
As the international community continues to monitor developments in Syria, the implications of this operation may resonate beyond the immediate area, influencing broader geopolitical dynamics, including U.S. support for allies in the region. For instance, recent developments regarding U.S. support for Ukraine may also reflect the complexities of U.S. military engagements abroad, as highlighted in recent coverage.
In conclusion, the destruction of ISIS weapons caches in southern Syria marks a significant achievement for U.S. and Syrian forces in their ongoing efforts to combat terrorism and restore stability in the region. Continued vigilance and cooperation will be essential in ensuring that such gains are not only achieved but sustained over time.



